1.) Login to the machine with the local administrator account or connect remotely from another server. 2.) Delete the profile for the user that's having the problem, i.e. C:\Users\User01 3.) Run Regedit, and remove the profile from HKLM>Software>Microsoft>Windows NT>CurrentVersion>Profile List>(SID) (you can right click on Profile List and do a search for the user name, i.e. User01. 4.) Once found delete the entire KEY for the user. 5.) Double check to ensure it's removed from System Properties>Advanced System Settings>Advanced TAB>User Profiles (Settings...) button> If you see the user in there, delete it too. 6.) Logoff as Local Admin and reboot. (Reboot not required but you may want to to be sure). 7.) Login with domain username.